Objectives: The aim of this study was to assess and compare the characteristics of commonly used initial arch wires by their load Deflection graphs.Materials and Methods: This study tested three wire designs namely copper nickel titanium (CNT), nickel titanium (NiTi), and multi-strand NiTi (MSNT) arch wires engaged in passive self-ligating (PSL) brackets, active self-ligating (ASL) brackets or conventional brackets. To evaluate the mechanical characteristics of the specimens, a three-point bending test was performed. The testing machine vertically applied force on the midpoint of the wire between the central incisor and canine teeth to obtain 2 and 4mm of Deflection. The force level at maximum Deflection and characteristics of plateau (the average plateau load and the plateau length) were recorded. Two-way ANOVA and Tukey’s test were used at P<0.05 level of significance.Results: Force level at maximum Deflection and plateau length were significantly affected by the amount of Deflection. The type of arch wires and brackets had significant effects on force level at maximum Deflection, and plateau length. However, the bracket type had no significant effect on the average plateau force.Conclusion: With any type of brackets in Deflections of 2 and 4mm, MSNT wire exerted the lowest while NiTi wire exerted the highest force level at maximum Deflection and plateau phase. The force level at maximum Deflection and the plateau length increased with raising the amount of primary Deflection, however the average plateau force did not change significantly.